Premieres Wednesday, Oct. 19, 2022 at 9 p.m. and Sunday, Oct. 23 at 2 p.m. on KPBS TV + Oct. 23 at 9 p.m. on KPBS 2 / PBS Video App. Mind-altering drugs—or psychedelics—have been used for thousands of years. Today, scientists are discovering their potential for profoundly positive clinical impacts, helping patients struggling with afflictions like addiction and depression.