email article As COVID-19 vaccination continues to roll out to older and medically eligible people across the country, many questions arise for those taking blood thinners. The most important point is that COVID-19 vaccine is fine for pretty much all individuals, no matter whether they have a thrombophilia, a prior deep vein thrombosis (DVT) or pulmonary embolism (PE), or are on a blood thinner. Reasons not to get the vaccine have to do with allergies but not with the fact that a patient has had a clot or is on an anticoagulant. While COVID-19 infection is associated with an increased risk of DVT and PE, particularly in the very sick and hospitalized patient, there is no reason to believe that the vaccine would increase the risk for blood clots. Recent concerns with thrombotic side effects after vaccination with the AstraZeneca shot in Europe appear to be chance events, not causally related to the vaccine.