Thereâs got to be an evil genius behind this. It just sounds too good to be true. The people who brought us the Wake Forest Innovation Quarter, Winston-Salemâs city-within-a-city, recently announced Phase II of their futuristic project. Set between U.S. 52 to its east and downtown to its west, the next stage envisions up to 10 buildings that will harbor new medical research facilities and mixed-use development â living and retail space â on a 28-acre site. More specifically, the plan calls for 1 million square feet of new clinical, laboratory and office space, up to 450 residential units and 30,000 square feet of retail and restaurant space that will echo what was built in Phase I.