4 March 2021 Reliable and accurate cell counts are crucial for many different purposes such as the maintenance of cell cultures in biological research or in-process controls in industrial bioprocessing. When considering currently available cell counting options, many users ask which cell counting method is better: manual counting or using automated cell counters. In this application note, anvajo GmbH demonstrate that the fluidlab R-300 can be successfully employed for automated cell counting across a broad range of cell types, including heterogeneous samples and small cells such as PBMCs and yeast cells.