email article Distinguishing between systemic signs of COVID-19 vaccination and symptoms of coronavirus infection in healthcare professionals receiving the newly authorized vaccine will depend on many factors, including type of symptoms and clinical judgment, according to the CDC. On a call with clinicians Monday, the latter were advised to pay more attention to those that were not reported as post-vaccination symptoms in clinical trials, but instead are linked with COVID-19 infection itself: cough, sore throat, shortness of breath, rhinorrhea, and loss of taste or smell. However, when it comes to symptoms such as fever, fatigue, headache, chills, myalgia and arthralgia, healthcare professionals (HCPs) must rely on their clinical skills and judgments about factors such as virus exposure and symptom duration and severity.