Ayako Inagaki, director of human and social development at ADB's Southeast Asia Regional Department Southeast Asian countries are facing a fresh wave of the coronavirus disease (COVID-19), mainly linked to new, more contagious virus variants and domestic and international travel. Adding to the challenge is the slow rollout of vaccination programs that are limited by supply in several countries in the region. Already, the pandemic has had a devastating impact on Southeast Asian economies, mainly because of mobility restrictions and border closures. The Asian Development Bank (ADB) is working closely with the region to battle the disease and identify opportunities to build a green, resilient, and inclusive recovery. Assistance has been provided through ADB’s $20 billion COVID-19 Pandemic Response Option (CPRO) announced in April 2020 to offer budget support to governments as they address the severe macroeconomic and health impacts caused by COVID-19. ADB is also supporting vaccine programs through its $9 billion Asia Pacific Vaccine Access Facility (APVAX), which was announced in December 2020 to help its developing member countries (DMCs) procure safe, effective COVID-19 vaccines.