Researchers Identify PH Probe for Dynamics Inside the Brain by Angela Mohan on December 28, 2020 at 12:00 PM Miniature pH probe helps in real-time investigations of extracellular dynamics in the deep brain structures. In our healthy brains, abnormalities in chemistry can lead to chronic brain disorders like mental illness, glioma, and seizures. Associating brain pH fluctuations with signaling and functions provides knowledge of the effect of pH on brain operations. In spite of technical progression in electrical recordings of the brain and chemical monitoring technologies, limitations remain in measuring the chemical signaling, especially the pH of living organisms, i.e. in vivo.