Revolutionizing drug discovery: The role of CRISPR gene edit

Target validation is a crucial step in pre-clinical drug discovery workflows that builds confidence on the identification of a genetic target as relevant to a disease. With recent advancements, CRISPR serves as a particularly powerful tool for this process, as it enables researchers to accurately modify genes and determine their function in a variety of experimental systems.

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Sergio Casas , Rinki Ratnapriya , Yu Holly Chen , Krishanu Saha , Panos Zalmas , Head Of The Open Targets Validation Lab , Wellcome Sanger Institute , University Of Wisconsin , Institute For Rare Diseases Research , Validation Lab , Baylor College Of Medicine , University Of Alabama At Birmingham , Editorial Article , Open Targets Validation Lab , Genome Editor , Thermo Fisher Scientific , Baylor College , Sergio Casas Tint , Drosophila Models , Human Disease Unit , Rare Diseases Research ,