Science Advances publishes proteomics technology from Obliqu

Science Advances publishes proteomics technology from Oblique Therapeutics AB


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Science Advances publishes proteomics technology from Oblique Therapeutics AB with a potential to bring several novel antibody medicines to large patient populations in multiple disease areas
Gothenburg, Sweden, April 16th, 2021 - Oblique Therapeutics AB, a Sweden-based biotech company, in collaboration with Karolinska Institutet (Stockholm, Sweden), Gothenburg University (Sweden) and several local biotechs published promising research results in the highly-acclaimed scientific journal
Science Advances (AAAS) entitled: Rational Antibody design for Undruggable Targets using Kinetically Controlled Biomolecular probes. The peer-reviewed article describes how Oblique Therapeutics´ Abiprot® technology can be used to discover and develop pharmacologically tailored antibodies against clinically important targets widely considered undruggable with antibodies. Two example antibodies are presented in the article. One is targeting hTRPV1, a clinically validated pain target. The second antibody is targeting KRAS, a highly relevant oncogene of critical importance in the etiology of many aggressive cancers (ex: pancreatic cancer). These early results have the potential to contribute to the development of much needed novel medicines across several therapeutic areas.

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