SEBiotic™ Receives No Objections Letter from FDA for GRAS Submission The Beneficial Research-Backed Bacillus coagulans Strain is Safe & Effective News provided by Share this article Share this article CHINO, Calif., Feb. 23, 2021 /PRNewswire/ -- Specialty Enzymes & Probiotics is proud to announce SEBiotic™ received a No Objections Letter from the FDA for its GRAS, which stands for Generally Recognized As Safe, submission. The GRAS Notification Program is a voluntary submission for products that are intended as food additives. Based on our extensive research, specifications, intended usage, history, preparation and reports, the GRAS submission for SEBiotic™ was reviewed by the FDA and granted a No Further Questions letter regarding its safety.