Several major freeway closures may add drive time this weekend KTRK Replay Video UP NEXT There are several freeway closures drivers can expect this weekend, but added traffic and a headache can all be avoided with these alternate routes we've suggested. Starting at 9 p.m. Friday, there will be a closure on I-45 North all weekend. The northbound lanes from IH-10 to Quitman Street will be closed until Monday at 5 a.m. Drivers are advised to detour using I-10 eastbound to I-69 northbound to I-610 North Loop westbound to I-45. Another big closure involves the Gulf Freeway. The southbound lanes from Nasa Bypass and Nasa Road 1 to FM 518 in Webster will be closed Saturday starting at 9 a.m. The southbound entrance ramp before FM 518 will also be closed.