SLO Brew downtown SLO location closes permanently and last updated 2021-02-13 02:25:22-05 A long-time Downtown San Luis Obispo favorite is closing its doors permanently. SLO Brew, also known as The Carissa, on Higuera Street has been closed down during the pandemic and will not return. Owner Hamish Marshall says the pandemic played a part in the closure. He says they decided to consolidate resources and focus on the SLO Brew Rock location and the Rod & Hammerâs distillery. The SLO Brew Lofts will still be open. KSBY spoke with a San Jose man who came specifically to San Luis Obispo to try local craft beer and was disappointed to find SLO Brew closed.