Intriguing Points: Cia Paranaense De Energia (NYSE:ELP). Imara (NASDAQ:IMRA) was the smallest company by market cap to set a new 52-week low. Provention Bio (NASDAQ:PRVB) saw the most downward movement, as shares plummetted 26.35% to hit a new 52-week low. The following stocks set new 52-week lows as of 10 a.m. ET on Friday: Cia Paranaense De Energia (NYSE:ELP) stock set a new 52-week low of $1.07 on Friday, moving down 2.69%. ACADIA Pharmaceuticals (NASDAQ:ACAD) shares were down 1.35% for the day, having made a 52-week low of $20.31. Vertex (NASDAQ:VERX) stock hit $19.39 on Friday morning, setting a new 52-week low for a change of down 2.84%.