Yes I have never thought about it in the past because I've never seen it as a physical disability so I never questioned it that I should apply for disability back holders but if given a chance I would certainly apply for blue badge you keeps National Executive Committee will hold an emergency meeting later to discuss the future of its leader Henry Bolton he's facing coast to quit after his former girlfriend was accused of making racist comments about Meghan Markle Turkey says it's a false hit more than $100.00 targets on the 1st day of a bombing campaign against Kurdish militants in northwest Syria and says dozens of warplanes were involved in the attacks on the militia in the African region and rebar he is a professor of international relations and I say it said made an alliance with their work against ISIS there's no question that they won their they can come back that if they wipe each year were to be defeated. So because why p.g. So far has been the only group that's been successful in fighting ISIS in that or off Syria the government set up a new body to manage large scale project we calls the office for product safety and standards will work with local Trading Standards teams to identify risks and will also take over the monitoring of goods imported from the e.u. After blacks it is the Small Business Minister under Gryphus the government is investing 12000000 pounds a year into this body we estimate that there will be approximately around 100 staff there are powers already in place for training standards to act when product saw 40 but what this new body will do is it will ensure that the know how and the technical expertise is available to prevent any delays and to keep the public as safe as possible Now let's cross live to Melbourne and get the latest on the strain Open tennis with the rest of the latter. We are 15 minutes away from the appearance of Kyle Edmond for his 1st 4th round match at the Australian Open he's up against Andrea Seppi of Italy who is trying to get a bit below him he's also 33 but he has to beat Roger Federer and Nick curious at this event in recent years rough on the dollar the world number one is on court at the moment and he leads Diego Schwartzman of Argentina for 3 it his 4th round match 2 results from the women's singles Caroline Wozniacki world number 2 is through she's beaten magdaléna or Barack over joined in the last 8 by Carla Suarez Navarro the rest of the sport in a moment 1st the cricket had a ring around. England 807-4322 overs have been bowled in this 1st innings in the past to bat 1st for the 1st time during this one day series victory today would see Morgan side taking on all say the 3 nil lead in this 5 match series the wickets to fall so far today Jason Roy for 19 Alex ales for just one and Jonny Bairstow for 39 at the crease at the moment Joe Root on 270 in Morgan the captain 11310743 after 22 overs is the score let's get the rest of the morning sport here he was in Croft Manchester United Tarion has agreed a move to Arsenal which will see Alexis Sanchez move to Old Trafford in exchange both players were missing for their side's Premier League wins on Saturday surgery where I hear how tricky Manchester City 31 victory over Newcastle Chelsea Stoke and Leicester all won but a West Ham against born with and West Brom's trip to Everton ended level Scarlett's be too long $3027.00 to become the 1st Welsh side to reach the last 8 of the rugby Champions Cup in 6 years however exits the chiefs of Bath and Ospreys a roll outs and there will be a 1st time winner of this year's Masters snooper event Mark Allen will face current Wilson in Sunday's showpiece at Alexandra Palace this is b.b.c. 5 live for us in the Premier League football and you want. That's the so I don't know whether it'll be a cold start for many rain in the Southwest will spread elsewhere or some snow in the north but coming drier later lows of minus one to be as an Edinburgh and 3 in Cardiff some as my spokesman for you know the Premier League 156 was crazy to see the light to close because 6 months the sizzix against little b.b.c. Radio 5. Should be. Sliced sees rising was 5 lines on Friday night sports extra 6 Christiansand ahead for breakfast from 6 o'clock but 1st we join Dr Chris Smith and the team for 5 Live Science this program is prerecorded so please don't call or text. Hello welcome to 5 Live Science I'm Chris Smith from The Naked scientists team and in the program this week a blood test that can pick up cancer we find out how flu works on the crabs that drum to attract to might Plus if you're going to put in a drink frenched and you need to not taste of anything and you need it to actually dissolve and that fluid if you're pitching and a fluid and you need it to not smale either or change the color of the drink very macabre we're looking for the perfect poison the make inside 6.5 was the 1st one in 3 of us will have a brush with cancer at some point in our lives and regrettably in the vast majority of cases by the time we discover we've got the disease it'll already be at an advanced stage and often that means too late for simple curative operations to remove it now though things might be about to change because Papadopoulos Johns Hopkins in Baltimore has come up with a way to test blood samples for proteins and d.n.a. Markers that can pinpoint the presence of early stage cancer in 70 percent of cases an easy. Than reveal where in the body the disease is the problem was the early detection of cancer we believe that detecting cancer early gives a better chance for survival of the individual has the cancer the standard now is to actually let the people present were symptoms go to the doctor and then the doctor has to treat situations which are like methods that the cancers can cancers of late stages we think that this approach to cancer has to change and we need to start from detecting cancers early which is much easier to read sometimes on who said that sounds like a very laudable I try to pick this up as early as possible but how what we're lectured to do was to develop at the chronology that can detect pieces of d.n.a. And proteins from cancer cells that are pleasant in plasma now or plasma our blood has a lot of d.n.a. And prodding but most of them come from normal cells so our task was to try to detect those traces of d.n.a. And prodding that come only from the cancer cells so you're looking for d.n.a. That spills out of damaged or diseased cells that are cancerous or potentially becoming cancerous that goes into the blood and you can pick that up and you're looking for proteins which are also spilling over from cancerous cells so this is a blood test for cancer anywhere in the body that is correct yes we called it immoral unallowed because we use more than one market yes how did you choose what d.n.a. To go after or what are the d.n.a. Signatures if you like that are the hallmarks that there is cancer somewhere in the body and it's getting into the bloodstream. There are a lot of studies with the sequencing of the d.n.a. From a lot of human cancers and that information distills down to a number of genes that are mutated those mutations are specific for cancer cells and not from normal cells so what we did was we took that all information with distilled it down to 16 genes and 61 regions of the genome that are commonly mutated in cancer cells and not in normal cells and we use that how do you know when the cancer is that because you've taken a blood sample from for instance the person's om blood goes all around the body could be seeing cancer cells anywhere so how do you know where the chamber is just on the basis of a blood sample because you use the information both from the d.n.a. That comes from the cancer cells and the proteins that they come from the kinds of cells that are actually it's a lot of information that and I'll go to them that we developed analyze this and they narrow it down to 2 different locations of where the body is and how sensitive is this How good are you at finding the needle in the high stack Yeah in this particular study you tested 1005 individuals they had 8 different 2 more types when we analyzed the blood from this individuals on average we were able to identify about 70 percent of the individuals that they had cancer so that sensitivity on average it's 70 percent and we were better in detecting certain to more types like ovarian and not as good at detecting other 2 more types and also we were better detect in a little bit later stage cancers than every state's cancers What about the false positive rate because the last thing anyone needs is to be told by the doctor or you might have cancer in fact they're perfectly healthy. Yeah that this is what it was and still is our concern we wanted the specifics of the to be at least 99 percent we detected 7 false positives out of $812.00 people presumably free of cancer as you said is very important not to what a lot of people they have cancer while they don't and all we far away from actually having a realizable test here with what you've done well obviously I don't know what far away is I hope that within the next the you know a few years the test will start being used but we have to be successful with the follow up studies Well let's hope they work it out Nic Papadopoulos there from Johns Hopkins describing the blood test for cancer that he's just announced in the journal Science now you've probably noticed that we are in the middle of a flu season but what is the flu and how does it work George Mills has the flu is flu a flu. Despite causing such big problems the influenza virus is tiny it's a spiky football about 110000th the size of a full stop comprising a package of genetic material protected by an articulate and once it's inside this little package packs a punch. But how does it get inside the flue is transferred from person to person 3 tiny droplets of liquid that you can then breathe in. A sneeze from an infected person can contain hundreds of thousands of individual virus particles and viruses can survive on surfaces like phones and handrails $5.00 to $2.00 days waiting to literally be picked up by you so if you come into contact with the flu and then don't wash your hands there's a high chance it will make its way inside she begin its dirty work. Like all viruses the flu cannot reproduce on its own it needs the cells in your body for that when the flu lands on a cell it's taken inside and then aggressively hijacks the machinery within and before you know it. The virus begins to multiply ultimately making thousands of new flu particles these spread and infect neighboring cells 1st also converting them into flu factories and then eventually killing them but these infected cells sound the alarm with a chemical signal that causes other nearby cells to go into lockdown making it much harder for the flu to get in. But these signals also lead to some of the flus nastiest symptoms like fevers aches and pains and fatigue. Some of the other symptoms like runny noses and block sinuses are also caused by your own body as it goes into defensive mode the mucus makes it harder for the virus to spread to other cells and other infectious agents trying to access your airways thoughted. As well as going on the defensive your body also prepare as a counter to. Your immune system learns what the invader looks like and goes on the offensive producing legions of antibodies and white blood cells to fight off. But unfortunately unless you've had the same strand of flu before it takes time for your immune system to take action which is why you can be bedridden for days. And for those of us who are over 65 pregnant or with a compromised immune system the flu compose a serious threat leaving you vulnerable to other infections like mania so when it's flu season it's best to sneeze into tissues and wash your hands regularly and if you think you have the flu don't go to work as you're most likely to pass it on in the early stage of the disease thank you Georgia and we'll hear a bit more about the past present and future of float through the program for that though this is. What happens when the science and technology space comes down to earth. Welcome to down to earth to make it scientists the mini series that explores the spin off from space technology that are being used on earth I'm. This episode how our space plasma trail being developed for Miles has already led to a more portable and efficient electric vehicle charger for use in the home. Is there life on Mars if there is it may well be hiding below the surface and scientists from the European Space Agency isa want to dig into the red planet on future missions to see what they can find however drilling deep underground is hard enough on earth let alone on other planets he says funded a Norwegian company to study a new drilling technique called plasma channel drilling which they hope will allow more efficient and deeper drilling on Mars plasma channel drilling was 1st developed by researchers at the University of Strathclyde in Glasgow it works by placing 2 metal plates on the surface of a piece of rock and applying a very short but very high power post of electricity between them the voltage between the metal plates can reach up to 50000 votes for the peak power of 100 megawatts that's the equivalent of a 1000100 watt light bulbs or be it for less than 50 Thousands of a 2nd the true head is surrounded by water and as the voters quickly ramps up something unusual happens rather than the electrical current taking a short cut through the water it sends out under these extreme conditions the right provides less electrical resistance a plasma channel was formed in the rock electrical current can pass through this plasma heating expanding it rapidly to cause the rock to break apart after the researches license out this technology was eventually picked up by a Norwegian company who are now a means to him into a viable space plasma trio for future missions in key to the effectiveness of the plasma trail is his power supply which needs to rapidly but she's poses a high voltage room in available power always limited on board spacecraft so this force the company develop a new form of electrical transformer Transformers essentially to quote was a wire wrapped around a common metal core and is used to send Lobo shes into high ones and vice versa the Norwegian company develops a new transformer design that both generates high vote she is and is also extremely compact and in doing so they realize that the same technology could be used to improve the way electric vehicles a challenge to home the company could reduce the size of a home car charger which is effectively a giant phone charge a fee a car for 100 kilograms to about 2 kilograms using the transformers it developed for space plasma drilling the new JLI Well the technology hasn't yet been. And space the spin off from it is already available to consumers back here on earth so that's how developing a space plasma true for Mars helped lead to portable home challenges for electric vehicles. That was down to earth when they could scientists My name is. Far more present online and make it science stop com slash down to earth. Thanks to its Now back to our flu and we're about to learn how flu is affected in the past Georgia mails again it may be a current problem but the flu is not a new disease Great Physician Hippocrates described the symptoms roughly 2400 years ago and epidemics which are severe outbreaks in communities a documented throughout history but sometimes a new strain of flu can go global and cause what's known as a pandemic. The 1st evidence of a pandemic was from 1580 but the most deadly and infamous one to date was 100 years ago this year the Spanish Flu This is been described as the greatest medical Holocaust in history killing more people than World War One in fact is estimated between 2.5 and 5 percent of the world's population dight and what made this pandemic especially unusual is that the victims were mostly young adults more normally flu is a major risk for the very young and the very old. Pandemics usually caused when a strain of flu affecting pigs jumps into humans These can then spread like wildfire because no one in the population is immune to them this is what was behind the Spanish flu pandemic and more recently the 2009 swine flu which came from you guessed it. Well flu pandemics occur around every 30 years none have been as severe as the Spanish flea perhaps in part due to the development of the 1st vaccine in 1938. Vaccines work by feeding your immune system small or inactive bits of the virus so it can learn what the agent looks like and be ready to destroy it should the infection being counted for real so if we have a vaccine Why does the flu keep coming back. Well this is because unfortunately flu is always one step ahead the virus graze rapidly and as it does so it regularly makes genetic spelling mistakes called me. These alter the appearance of the virus as it spreads through the population giving it a molecular facelift that means the immune system will struggle to recognise it later RINGBACK. This is why you need a new flu jab every year because the vaccine is constantly being checked and updated to make sure it provides protection against the secular eating strains of flu you're most likely to encounter that because vaccines need to be made ahead of flu season scientists actually have to predict what the flu strains are going to look like when they do arrive most of the time they do get it right but sometimes the virus behaves unexpectedly meaning the vaccines aren't fully effective and later we find out about this year's flu and how worried we should or shouldn't be you listening to 5 Live Science with me Chris Smith still to come we see if there's any such thing as the perfect poison the miles of many species go to extraordinary lengths to try to might for instance peacocks invest heavily in impressive plumage Lions grow a massive mane and humans pay for dinner or at least pretend that they like cats for the crabs on the other hand or should that be clor grow one very large pincer but they drum against the grounds to attract female attention talking to Katie Hiler Sophie moles from Ruskin University has discovered that for these fiddler crab's timing is everything. The display of the male fiddler crab actually serves to advertise his physical fitness so they not only weigh fest close but there was a drug meant remand to k. These because of crabs make sweet music by drumming these enormous close vigorously against the leg the vibrations carry through the ground getting the attention of the females. What we found was that the males that waved and drummed more vigorously had better performance so we actually put them in Sprint trial as we made them run. So you race cross is a nice way to show whether stamina has been depleted is the logic to this then if I can wave my Big Claw more quickly I'm fitter therefore I'm going to be a better match for you exactly that a better male firstly that his book at genes may be he is just genetically physically fit and if he's fit enough to perform this waving display then he might be fit enough to run quickly from a predator or to defend his territory or to forage effectively and these are all things that the female should want to provision her offspring with genes for his characteristics. So vigorous wavers were fit a way that is good genetic news for potential offspring but it's not just fast waving that gets female fiddler crab's heart's racing it's fast waving that is getting faster still slowing down you're waving my indicate fatigue where is waving that is gaining tempo indicates energy to spare and more interest. Become the female crabs pick up on this increase in waiting pace and how do you test this will suddenly male crabs are easy to train Sophie says so she and