scale in the process development, all the difficult stuff, is maintained. i listen to sara gilbert's dimbleby lecture and i know there are funding struggled to maintain the vax labs, which was the very reason they were able to get out of the blocks quickly. so we need to look very hard at the capability distributed around the uk, notjust oxford, so that we can act quickly as and when we need. i think another group that came out very positively lusty was the cpi, the centre of process innovation, the centre of process innovation, the high value manufacturer in darlington. they were taking novel manufacturing approaches and industrialising them, so that is a group which i think should be