As the nationalists sinn fein take the biggest share of the popular vote. This is bbc news. The headlines at eight. Four cases of coronavirus confirmed in the uk. Its now been irish Prime Minister leo varadkar says his fine gael will not be taking part in any Coalition Talks. Closed. Experts say there is and in the other major upset, opportunity to contain the disease. The south korean film parasite the detection of the small number of becomes the first non english language film to win best cases could be this part that becomes a bigger problem. For now, picture at the oscars. Its only this part. I dont want to hello. Im katty kay in New Hampshire and Christian Fraser is in london. For a while Pete Buttigieg was the young mayor with an unpronounceable name, go back to prison. A year after from a small town few people had heard of, and he got largely ignored by his fellow democrats who were running to be president. Being cleared of a sword attack that has all changed. Outside buckingham palace. Cleaning last night mr buttigieg up outside buckingham palace. Cleaning up the mess again. People across was formally, finally, england are angry as a flood declared the winner of the iowa caucus and the other candidates seemed to wake up defences flood to the realisation he is a real threat who needs taking down. So the attacks began. Its not personal its what happens in american politics when youre a front runner. But it was noticeable how much the tone sharpened this weekend amid anxiety that democrats are struggling to find a strong candidate to run against donald trump in november. Forget the kumbayah of a few weeks ago, this is what the democratic race sounds like now. He is no barack obama. He is right, im not, and neither is he. Going after every single thing that people do, i dont think thats what people wa nt do, i dont think thats what people want right now. We have a new, in the white house and look where it got us. This is going to take sucking up to billionaires or being a billionaire to get the democratic nomination, to run for president , then all i can say is buckle up america. Bernie says you have to bring people together, and we have to have medicare for all. But he doesnt say how much the damn thing will cost. Unlike some appear, i dont have billionaires contributing to my campaign. The tone of it gives you the sense of how important New Hampshire is. With me now is Holly Shulman spokesperson for the New Hampshire democratic party. Thanks forjoining me. After the chaos of iowa is New Hampshire going to give a clean result that will help narrow the field . Its very different from the caucus system in iowa, people show up and they are given a ballot, they mark it, it is counted and that is it. So we will have a result tomorrow night. Does the tone we have seen over the course of this weekend reflect how important the candidates think New Hampshire is . Definitely. We are the first people to cast our ballots so New Hampshire citizens take this very seriously. They know the responsibility they have and they know their vote matters. If the candidates dont do well here in New Hampshire, what does it mean for theircampaign . Takejoe hampshire, what does it mean for their campaign . Take joe biden, hampshire, what does it mean for their campaign . Takejoe biden, down infour in their campaign . Takejoe biden, down in four in iowa. There are four early states, so the candidates will have two more chances to prove themselves and then we will see what happens. In New Hampshire we are still looking at it being anyones game. 49 are still undecided, according to the last poll i saw. The tone of the last few days, is it helpful to democrats as they take on donald trump or should they be focusing their attention on donald trump . We saw over the last few yea rs, if trump . We saw over the last few years, if you are here in 2016 it has been a much more Divisive Campaign to what we are seeing now. I think when donald trump shows up tomorrow night, people will regain their focus and know that this election is about him, his broken promises and contrasting that with democrats who have a vision to move oui democrats who have a vision to move our country forward. How soon do the democrats need to come up with a candidate to rally their party around . We have lots of possibilities, people are excited about the choices we have. What i hear from democrats is about the choices we have. What i hearfrom democrats is they about the choices we have. What i hear from democrats is they are anxious. I know how important it is to beat donald trump so people are worried about who is the best candidate to beat him. Electability is ranking at the top of the list this week but we will have a nominee 0011 this week but we will have a nominee soon enough. The forecast is not great for tomorrow, it was drizzling and snow when i arrived. Turnout matters for democrats, it was not high in iowa. I how good is turnout going to be tomorrow if we get more rain and snow . turnout going to be tomorrow if we get more rain and snow . I will say New Hampshire folks go around in snow all the time, it is i see all the time. Do you get a sense of what we saw in iowa aware that democrats are tired and exhausted by politics at the moment . I think people are tired but they will still vote. People know that this matters and they will be there. 0k, thank you very much. Very diplomatic, very confident. It is important for democrats to get out and vote, it is a big election and turnout has to get up. It has to be better than it was in iowa. Some news from the Bernie Sanders camp, formally requesting a recount. Maybe we have already moved on from iowa anyway, it is all about New Hampshire this week. This is how the poll looks. This is what Pete Buttigieg was looking like at the beginning of the week. You see the vote was on the fourth, so 1796, see the vote was on the fourth, so 17 , and its been rising all the way up through the week. The little dip is probably because those in the middle, the centre ground, are torn, but as they told us last week roughly a 10 bump when you win iowa. Which given that we only got the official result last night is remarkable. Democrats had not really heard about this mare from south bend indiana, and now he is the guy to beat. This is still Bernie Sanders state, it is the state he w011 so sanders state, it is the state he won so resoundingly last time around. Sanders is still the guy who is the frontrunner, but the fact that Pete Buttigieg and notjoe biden is the candidate everyone is talking about, the centrist candidate, i think is indicative in and of itself. I have spent the last few days talking to democrats in washington and they are really nervous, concerned that their front runners at the moment are not candidates they feel are solid to ta ke candidates they feel are solid to take on donald trump. There are too many negatives about Bernie Sanders and Pete Buttigieg, too new to the game, and biden seems to be disappearing. So early in the race, but the pivotal day tomorrow. Lets turn to coronavirus. There are four newly confirmed cases of coronavirus in the uk, and two of them are Health Care Workers. Two Health Centres one in brighton and one in northamptonshire have closed as a precaution. The four people infected were all in contact in recent weeks with a businessman who contracted the virus at a conference in singapore, and was diagnosed in brighton last week. So, is it spreading more widely . And can it be effectively contained . We have gone back in time to monday 20th jan when the who first began tracking and publishing a tally of those infected. Here are those same stats a week later. By the third february there had been quiteajump. But todays figures show a significant increase, more than 40,000 infected, 910 deaths and 97 of those deaths have come in the last 2a hours. We can speak to lauren sauer, assistant professor of emergency medicine atjohns hopkins. Shes an expert on preparing for critical events. And with me in the studio, peter 0penshaw an immunologist and expert on experimental medicine at Imperial College london. Lauren, cani lauren, can i start with you . We have eight cases now confirmed in the uk. The government today deemed the uk. The government today deemed the virus is a serious and imminent threat. Is it spreading . Yes, i think we knew it would be spreading. Some people are calling them super spreading events and any time you see Health Care Workers getting infected you can be sure you will see more spread. Peter, letsjust talk about this business men. He comes back from a conference in singapore and he goes to a chalet in chamonix, and all told he has infected 11 people and they are calling him a super spreader. With normal flu, if you calling him a super spreader. With normalflu, if you had a cold calling him a super spreader. With normal flu, if you had a cold you would in infect one or two people, so does this virus spread more easily or is in more contact with people . What do we know . M more easily or is in more contact with people . What do we know . It is a controversial term, super spreading. It was kind particularly in relation to the sars outbreak in individuals infecting a lot of people, because they were in a e departments and needed intubation which meant they were exposing a lot of people to their secretions. It looks like this particular individual seems to have been able to get around and behave relatively normally, maybe even go skiing, yet has been able to infect a large numberof has been able to infect a large number of people. Its a matter of how much virus is being produced and how much virus is being produced and how easily it is contaminating other people. There are so many things we dont know about how the virus spreads and why it is some people seem spreads and why it is some people seem relatively unaffected personally, but seem to produce a virus that goes on to affect other people. Lauren, you dealwith emergency responses to this kind of thing. Let me clarify about the masks, how effective are they . We know a lot about masks but one of the things we have been seeing in this outbreak is people Wearing Masks who are otherwise well. What the who do not recommend is using masks is a well person to protect yourself from the virus. Masks when yourself from the virus. Masks when you see them in a health care environment, for example during flu season, it is for patients with respiratory infections to prevent them from potentially infecting other people. Health care workers wear masks because of their prolonged exposure to patients who are sick. Masks in well people is not recommended, it is not evidence based. We dont have science that supports their use and may potentially do harm in people who are having respiratory responses. My second question is how smart is it to be incubating people, isolating people on these cruise ships . Yes, the cruise ships are a really challenging question. Obviously they spread virus pretty easily, we see that in the regular norovirus outbreaks on cruise ships. From what i understand these people are isolated in individual rooms. The sick people are separate from the well people so the well people have been quarantined and they are kept separate as best as i can understand. Ideally you want to get eve ryo ne understand. Ideally you want to get everyone off the cruise ship and into ca re everyone off the cruise ship and into care or home quarantine as soon as possible. There is a woman who has been taken to a japanese hospital and she has got coronavirus but she has not shown many symptoms. Her husband who slept in the same bed, he is not showing any symptoms and has not got it at all. There is so and has not got it at all. There is so much we dont know about how this virus is spreading, what it is that makes one person susceptible and another not. It may be that we all carry genetic variations in our immune system which will defend us against viruses in different ways and we are just learning so much. The opportunity for doing some really important research, not only in countries and cities where there are a lot of cases but also for example in cruise ships so we can really understand this well is extraordinary, and the rate at which china is coming out with wonderful Research Findings which really helped us understand virus is remarkable. Peter, is it the speed at which this virus is spreading or the lethality of the virus itself once people have it that concerns you the most . The impact of any pathogen is a product of multiplying the speed at which it spreads by the danger that it creates for the individual. In this case it is spreading much faster than the sars virus in 2002, 2003. It was possible to defeat that but it was a severe pathogen. This seems to be less lethal but a much better spreader. The result of the high number of people plus the appreciable lethality is the thing we are concerned about. We have been carrying covering this for weeks now, and it estimated 1 of those infected die, so that is on a par with seasonal flu. Are we blowing this out of proportion . The death rates, estimates are just that, estimates. We dont know a lot about this virus or the more in mild cases so this virus or the more in mild cases so hopefully we will see the death rate drop. We often tend to compare risk of well known things like flu with unknown things like this coronavirus because it helps us put that risk into context. That can be troublesome because there are things about flu that are very different. We have good diagnostics, we have vaccines to varying degrees of success , vaccines to varying degrees of success, and we know how to manage flu cases. We practice for it every year. Even pandemic flu cases we can learn a lot from our seasonal flu management. In this case with all these unknowns it is a different threat, and that is what is driving the more extreme measures of precaution happening now. Very quickly, peter . I agree. What is frightening about this is the unknowns, and also it is a protracted disease and the deaths are occurring at week three. With influe nza are occurring at week three. With influenza it tends to be won in 1000 or less, and here the mortality of one in 100 is really very high. Fascinating. Thank you both for your thoughts. But to clarify all of that. Good to clarify all of that. In china counting the cost of the disease goes far and wide xijinping said his government will work to prevent large scale lay offs. Many in china were due to return to work today after the Lunar New Year holiday, but much of the country remains closed to contain the virus spread. The Economic Cost has mounted as shutdowns in the country continue to disrupt Global Supply chains. Our economics editor faisal islam reports. It should be back to work in china. After celebrating chinese new year, tens of millions of workers were expecting to have returned to the cities and to the factories, one of the fundamental drivers of the world economy. But the commute is so far is quieter than usual and in the offices that are reopening, its anything but normal. Translation our company has adopted special measures, including sanitising every day. The building is in isolation. We are required to wear masks the whole day while at work. In the shops, food prices have surged, up 20 on last january. Pork prices have more than doubled, at the same time the economy is slowing. The actual Economic Impact will depend, of course, on the Global Health impact. What we do know is the virus, and measures to contain it, have led to many factories remaining closed today that should have reopened by now. Slowing chinese demand for luxury goods and crude oil, as well as reduced chinese tourism abroad, and some supply chains for key parts manufactured in china are broken, with many global businesses seeking alternatives, for example in vietnam. The already weak chinese economy is expected to see the slowest three months in over a decade, possibly a contraction, and in turn that could see the same for the entire world economy, an immediate global hit worth over £200 million. Worth over £200 billion. The expectation that this will be made up over the rest of the year when, or if, things get back to normal. That can be seen even 5,000 miles away in this yorkshire electronics factory, dependent on components shipped in from shuttered plants near the centre of the outbreak. We have been able to find alternative sources for the materials, but because we need them quickly now, then there are price implications and some of that has been as much as three times the original cost. There has been major disruption likely to delay recovery in an already fragile world economy. President xijinping, appearing in beijing in a protective mask, says if the virus is contained, the impact should be temporary. But that is not certain right now. Faisal islam, bbc news. That Economic Impact spreading around the world. There has been an earthquake in irish politics. Sinn fein, known historically as the political wing of the ira and a party that for a long time was shunned by the political establishment is now the biggest in ireland. They won the popular vote in this weekends election beating both fianna fail and fine gael. The two centrist parties that had governed ireland since the republic won independence a century ago. Sinn fein won almost a quarter of the first preference votes but are unilkely to hold the most seats in the parliament. Michael martin who leads fianna foil the party that came second has not ruled out working with sinn fein. The current Prime Minister leo varadkar who leads fine gael came third. Hes ruled out any Coalition Talks with the nationalists. Una mullally. Which way do you think this will go . Who knows . We are now in Uncharted