Including lean on me, lovely day and aint no sunshine has died from heart complications. Hello, good afternoon. The first of the nhss Nightingale Hospitals has been opened, set up to expand capacity during the coronavirus outbreak. Its been built in less than a fortnight, inside the excel Conference Centre in east london, and the first patients are due to arrive early next week. It comes as the uk records 684 coronavirus related deaths in a day. Its the highest rise so far, but slightly below the expected trend. The death toll now stands at 3,605. Meanwhile, from self isolation the Prime Minister took to twitter to urge people to stay inside this weekend mrjohnson also said he would continue his isolation as he still has a fever. And more messages of support on their way, as its announced her majesty the queen has recorded a special broadcast to the nation, which will go out on sunday evening at 8pm. More on that soon, but first, our correspondent Angus Crawford reports on the opening of the first Nightingale Hospital. Ladies and gentlemen, as the wonders of modern technology can only do so much and i cant quite reach, perhaps i can invite nightingales head of nursing natalie gray on my behalf to unveil the plaque to declare nhs Nightingale Hospital open. Applause. A royal opening from lockdown. At his home in scotland, Prince Charles still recovering from the virus paid tribute to staff here and around the country. Everyone can now have the reassurance that they will receive all the necessary technical care they may need and every chance to return to a normal life. This hospital, therefore, offers us an intensely practical message of hope for those who will need it most at this time of national suffering. An empty shelljust days ago, look, an army of civilian contractors and the military have built nightingale from scratch wards stretching the length of the building. 500 beds to start with increasing to a total of 4,000 if needed. At that point, 16,000 staff would be needed to run it. 0nly patients already on ventilators will be admitted. The first should arrive in the coming days. The idea was dreamt not long ago of having a new hospital. And this london nhs Nightingale Hospital, which was put together, its core, in nine days, is a testament to the leadership of the people who stand behind me. This may eventually become the biggest hospital in britain. Its an extraordinary achievement to have created it in less than two weeks. But, now its open, medical staff have to ready themselves for the harsh reality. The waves of patients that may come in the weeks ahead. Its now become the model for other nightingale units being set up across the country including in birmingham, bristol, cardiff and glasgow such is the concern about the potential spread of the virus. There are questions, though. Will the unit get enough equipment and staff . And how will they cope if and when the wards start to fill . For now, though, nightingale stands open and ready. Angus crawford, bbc news. 0ur Health Correspondent lauren moss is here. First of all, just run us through the latest figures on overall cases in the uk . There are m50 new cases of coronavirus in the uk, confirmed up of coronavirus in the uk, confirmed up to nine oclock this morning. A total of 38,168. That is the largest increase in a single day but also more tests have been carried out as well come at an increase of 10,500 tests, the largest we have seen in a single day so we would expect those positive number of cases to increase. Around 40 of people tested, their test result came back positive. If we follow the trend over the last few days, it has been climbing. We can show graph that shows the number of cases have been on the up after a dip at the weekend. Following that throw, we could have seen over 5000 new cases today and its less than that by around 500,500, today and its less than that by around 500, 500, so this could provisionally suggest numbers of slowing down but of course, 10,500 people tested. Nhs staff now among those, so we would have expected the sorts of numbers. It doesnt also assume that everyone who has symptoms has been tested because we are only testing people in hospitals and nhs staff who may have symptoms 01 and nhs staff who may have symptoms or live with people who do. An epidemiologist says its possible the figures will rise again but that could be down to more testing rather than more cases. And the daily death toll for the last 2a hours, again, the highest we have had so far . 684 deaths recorded in the uk in the last 24 hours, up to 5pm yesterday. That is the largest number in a single 24 hour period. The number of people dying has been increasing every day, doubling roughly every three and a half days. 3605 people in total now. But with that in mind, what we have seen today in what we have seen over the last few days with the increase in deaths, that is what we would have expected if you are taking into context the rate over the last week or so. So although these numbers are very stark and these people were talking about, they are not numbers just on graph but the deaths are what we have been warned to expect. They are not higher and they are not lower. Very sadly, some of those deaths also include Health Care Workers . Just two of the very sad accounts we are hearing today, 39 year old nurse in kent died after testing positive. Amy orourke died in margate last night. She was a mother of three. The hospital staff spoke very movingly about her today, saying they are devastated, she was a valuable part of the team and it was an honour to work with her. Another nurse we have been told about in walsall nurse we have been told about in wa lsa ll was nurse we have been told about in walsall was 36 and died in intensive care. The head of the trust there had said losing one of their own is beyond words and that she was a very committed staff nurse. Throughout the hospital this morning and prior to this morning, there is a huge amount of anxiety and a lot of psychological distress, i guess. Because staff are dealing with, day in, day out, people who one minute are ill, but alert, and the next minute deteriorate very, very rapidly indeed. And areemas death has hit her colleagues on the acute medical unit, colleagues who were lacking looking after her in intensive care and the wider organisation extremely hard this morning. So although the number of people dying with coronavirus and the number of positive tests are still climbing, it is still too soon to say exactly when the people hit exactly. Matt hancock didnt want to be drawn on that specifically but the data will be played out over the coming days as more people are tested. Thank you for that update, oui tested. Thank you for that update, our Health Correspondent lauren moss. The Health Secretary matt hancock has admitted that meeting a target to test 100,000 people for coronavirus in england by the end of this month is a huge undertaking. The target was announced yesterday, after criticism that not enough frontline nhs staff were being tested. Labour has called for more details about how the goal will be achieved. Richard galpin reports. The country is potentially facing the biggest challenge of this outbreak so far. The peak is expected in just over a weeks time on easter day, and already infections are surging, doubling every few days, leaving thousands of people in hospital. Testing people for the virus is vital. Key workers including nhs staff can find out if they are clear to go to work without the fear of spreading the infection. But the government is facing sharp criticism for failing to scale up the Testing Programme quickly enough. And yet suddenly it has now announced it is aiming to increase testing from around 10,000 people a day to 100,000 by the end of the month, raising yet more questions. But the Health Secretary is determined to make it happen. Well, we have got to. It is a goal and ive set it for the whole system. The 10,000 a day that we reached on target was from the Public Health england and the nhs working together incredibly hard, firstly to develop the test we were one of the first countries in the world to do that and then to increase the number. For those on the frontline in the battle to save lives and defeat the coronavirus, maximising testing could make a big difference. It cant come quickly enough. You know, we are talking to hospital and other Health Service chief executives every day, and the issue of staff absence is huge for them. Staff themselves really want to get back to the frontline and Hospital Leaders really need those staff on the frontline. To reach 100,000 tests a day will require a massive effort involving industry and laboratories from all around the country including these recently built mega laboratories. Those in charge of this ramp up claim there will soon be an exponential increase in the number of people being tested. The test currently in use is a swab test checking if the person has the virus. There is also a blood test which can prove if someone has previously had the virus and, therefore, may have some immunity, but it has not yet been approved for use. The most extravagant claims of some of the manufacturers are for about 90 specificity which means that we would still have about one in ten positives that would be a false positive which means that somebody could be given a certificate of immunity when they were not really immune, but because of that being the nature of those kind of tests, we may need to learn to live with that degree of risk in the future. With the peak of the epidemic now just days away, it has been announced that more conference halls and other buildings like this one here in bristol, are to be converted into field hospitals. There will be at least six around the country, providing thousands of extra beds. A measure of what this country could soon face. Richard galpin, bbc news. One person who has been writing about what tests the world needs to track the pandemic is science editor of the financial times, Clive Cookson we can speak to him now. Clive, you have been looking at this for quite some time and can you a nswer for quite some time and can you answer the question as to exactly why the uk is lagging behind countries like south korea and germany, which seem to be so far ahead . It is partly because the uk has adopted quite a centralised policy. From the start, the nhs and Public Health england insisted on keeping control and the early testing was all done in the Public Health england lab. 0nly testing was all done in the Public Health england lab. Only recently, only within the last two or three weeks, have they realise that their own facilities are far too small and decentralised bringing in a lot of other laboratories, university labs, other laboratories, university labs, other labs, private labs and now building these three mega labs in milton keynes, manchester and glasgow. In contrast, germany has adopted a much more decentralised approach and that has been able to mmp approach and that has been able to ramp upfar, approach and that has been able to ramp up far, farfaster. Also, germany has a stronger biomedical industry. There are more diagnostics companies. So i think it probably had a head start, in terms of its own industrial capacity. But i think if england or the uk had geared up more quickly, we could have been in a better place now and not scrambling to catch up. In fact, we had much more capacity than Public Health england used at the beginning . Thats right. And what would have been really good would have been if, near the beginning, wed done, as i think germany did, built upa wed done, as i think germany did, built up a good stockpile of the supplies. Now the supplies, notjust the chemicals and reagents needed to carry out these tests but the other things, the swabs, the special Precision Plastics needed to build the kits, those are in huge worldwide shortage. If we had started building up supplies earlier, we wouldnt be in such a mess. Weve certainly got the capacity now. I think everyone in the industry says with the mega labs, this new collaboration with universities and private labs, we have enough capacity. The question is if we will have enough equipment, rea g e nts is if we will have enough equipment, reagents and kits to make use of it. Bearing that in mind, how realistic is the Health Secretary cosmic announcement of 100,000 tests a day by the end of the month . It is realistic if the supply chains commit. It is realistic. We have the staff. We have tens of thousands of committed scientists and researchers, many of whom were doing other things until very recently. They are all there and in place. Its so hard. Ive been trying to identify where these shortages are and its such a multifactorial problem, you cant say reagent x or reagent y is going to be running out. So its possible. I should also say that they are saying that the 100,000 willjust be on tests to tell who is infected. If we get the new sort of test, the Antibody Tests that show who has been infected in the past, that will be an extra. They are not relying on these Antibody Tests, of which they have bought millions, but they are not sure yet how well they work. We will have to leave it there, thank you very much for your time. Clive cookson, the science editor of the financial times. Thank you. Its just past four oclock. Youre watching a bbc news special on coronavirus. In around an hours time, were expecting the daily update from downing street. Lets have a look now at that video from the Prime Minister released on twitter, where he revealed he is still suffering from a temperature, after being diagnosed with covid 19, and will therefore remain in isolation. 0ur chief Political Correspondent vicki young is in westminster. We have seen the Prime Minister once 01 we have seen the Prime Minister once or twice in self isolation. He was sounding quite hoarse im not looking great, perhaps worse than before. We have seen pictures of him using the remote cabinet, that meeting with all of them doing it remotely. And his personal messages he has put out. But in some ways, he is trying to lead by example by saying, i have done my seven days in isolation, but i still have mild symptoms and a temperature and the guidance very clearly is of course if you still have some of the symptoms, you must stay away from others. That is what he is doing even though he is the Prime Minister. Downing street at pains to say these are mild symptoms and that he is still working. He has been chairing that morning meeting they have every single morning and he has attended remotely the cabinet meetings. And he is keeping in co nsta nt meetings. And he is keeping in constant touch with colleagues. But it must be difficult. We have had the Prime Minister in isolation, until yesterday, the Health Secretary, the chief medical officer also, it will make things much more difficult to coordinate, but the clear message from the Prime Minister is, i am doing it the way it needs to be done even though i am the Prime Minister, i am trying to leave the country during a time of national crisis, but you must still stick to these rules. The other a clear message from the Prime Minister in that video was telling people to stay at home this weekend even though the weather is going to be fine, he once ordinary people to stop doing ordinary things. Yes, there is real anxiety about this because even though children have been off school in the sand schools have been close, a lot of them have been set work by their teachers and have kept themselves busy to a point, but the easter holidays are starting and children of course will wa nt to starting and children of course will want to go outside as well others especially if the weather is good, so especially if the weather is good, so there is some concern people might think we are coming two weeks into these new restrictions, the weather is good, spring is here, we wa nt to weather is good, spring is here, we want to get out of the house a bit more. The guidelines are still you can go out to exercise, but they dont want people going out for the entire day and mixing with us, beyond theirfamily entire day and mixing with us, beyond their family group. They certainly dont want people getting into the car and driving to beautiful parts of the country. We saw that a couple of weeks tends ago, and the police trying to clamp down on that. That is the anxiety for this weekend a couple of weekends ago. And also going into the easter holiday. We have to be that there, vicki young, thanks very much. As youve heard, the queen will address the nation on sunday over the Coronavirus Crisis. 0ur royal correspondent Nick Witchell is with me now. Very unusual times. Broadcast is this, distinct from her Christmas Day message, reserved for message moments of Real National significance. There have been a handful of them during her 68 years. We remember the live broadcast from the eve of the funeral of diana princess of wales or 1991 as british troops went into action in the gulf war. Close consultation between downing street and Buckingham Palace over the past couple weeks and it was certain she would make a broadcast at some point. It is recorded and it will go out at 8pm on sunday evening. And i am sure it will embrace the themes she set out in the written Statement Issued on the 19th of march when she talked about a period of great concern and uncertainty, the emphasis she s