* Initial off-label-use applications with a special plasma design are promising. * Possible use in intensive care medicine and treatment of long COVID. * Planned large-scale study on universal use against coronaviruses and other RNA viruses. The life science company System4 Technologies GmbH has developed a new therapy device for the treatment of Covid patients. The device, named PI-RNA, is designed to enable universal and fast deactivation of coronaviruses and influenza viruses, their mutations and new variants by means of a special cold atmospheric plasma procedure. "The so-called CAP (Cold Atmospheric Plasma) - technology transfers electrostatically atmospheric anions, in high numbers and densities, into and around