Vaccine Uptake Requires Early Education to Build Trust and Ongoing Outreach to Ensure Follow Through Vaccine Uptake Requires Early Education to Build Trust and Ongoing Outreach to Ensure Follow Through Shipping COVID-19 vaccines to provider organizations is an immense logistical challenge. Health systems and physician clinics face their own challenge of logistics with limited resources: Educating patients about authorized vaccines, persuading them to schedule two timely visits, and reminding them to show up both times to receive the required doses. Upfront Healthcare, a leading omnichannel communication and patient engagement platform, has developed a digital vaccine program to meet this challenge head on by directly connecting with each patient. Upfront developed messages that explain the science of the vaccines. These messages use health communication principles to build trust and overcome obstacles stemming from various patient beliefs. This content informs patients about authorized vaccines and the distribution process before they are eligible to receive a vaccine, and then prepares them to receive the first dose. Upfront also provides scheduling and patient recall for each vaccine appointment and follow-up messages to check in after each dose.