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Novartis Pharma AG: Novartis announces iptacopan met Phase II study primary endpoint in rare kidney disease IgA nephropathy (IgAN)


Novartis Pharma AG: Novartis announces iptacopan met Phase II study primary endpoint in rare kidney disease IgA nephropathy (IgAN)
3-7
C3 glomerulopathy
Basel,
2
1 - Novartis today announced Phase II primary endpoint data showing investigational iptacopan (LNP023) - a first-in-class, oral, targeted factor B inhibitor - reduced protein in the urine (proteinuria), an increasingly recognized surrogate marker correlating with progression to kidney failure
2, and showed promise in stabilizing kidney function in patients with IgA nephropathy (IgAN)
1. The data were presented at the 58
th ERA-EDTA Congress held virtually from June 5-8, 2021.
In the Phase II study (NCT03373461), patients (n=112) with IgAN were randomized to placebo or different doses of iptacopan ....

Czech Republic , United States , Isabella Zinck , Thomas Hungerbuehler , Van Praet , Jonathan Barratt , Samir Shah , Jamie Bennett , Julie Masow , Sloan Simpson , Phil Mcnamara , John Tsai , J Nephrol Renovasc , University Of Leicester , Head Of Global Drug Development , Novartis Institutes For Biomedical Research , Novartis Us External Communications , Exchange Commission , European Medicines Agency , Renal Medicine , Leicester General , Global Drug Development , Chief Medical Officer , Therapy Designation , Novartis Institutes , Biomedical Research ,

Parteien in Mettmann: Wie sehr pokern bei Grünen die Generationen ?

Die Grünen sind mittlerweile die zweitstärkste Kraft in Mettmann und müssen den Ausgleich zwischen den Partei-Generationen schaffen: Grund genug für einen Hausbesuch. ....

Nordrhein Westfalen , Heike Ogan , Party Has , Ewa Bacon , Mettmann The Greens , னோற்ர்ேன் வெஸ்ட்ஃபாலன் , கட்சி உள்ளது ,

Petco got $875K to bring 400 jobs to San Antonio. They failed, but the city won't ask for refund


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Petco got $875K to bring 400 jobs to San Antonio. They failed, but the city won t ask for refund
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District 10 Councilman Clayton Perry.Kin Man Hui /Staff photographer
Petco Animal Supplies fell short of the 400 jobs the retailer promised San Antonio leaders when they gave the company an $875,000 tax incentive package to build an outpost on the city’s West Side 10 years ago.
But San Antonio won’t be asking for its money back. By a 9-2 vote Thursday, City Council decided not to claw back more than $500,000 in tax breaks and grant dollars it’s already given to the San Diego retailer. ....

San Diego , United States , San Antonio , Manny Pel , Clayton Perry , Erik Walsh , Alex Lopez , Manager Erik Walsh , John Courage , Ana Sandoval , City Manager Alex Lopez , Manny Peláez , Clayton Perry , Erik Walsh , Alex Lopez , John Courage , San Antonio , West Side , San Diego , District 10 , District 8 , City Council , Xpressnews Com , சான் டியாகோ , ஒன்றுபட்டது மாநிலங்களில் , சான் அன்டோனியோ ,