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New Research Outlines a Critical Driver in an Immune Cell's Defense against Melanoma

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Today in
, researchers at Huntsman Cancer Institute at the University of Utah report critical new insights into how cells mount an attack against melanoma tumors.
Melanoma is an aggressive type of skin cancer that can arise from excess exposure to sun, frequent sunburns, genetics, and other environmental factors. Melanoma, like all cancers, begins within cells. Specially designed and refined over billions of years, cells are experts at working to root out and fix routine errors that arise. A tumor begins when a cell makes faulty copies of itself over and over again. If left unchecked, these faulty cell copies continue to grow into complex ecosystems that become tumors. Some tumors, like melanomas, can go on to develop mechanisms to sustain themselves with blood flow and oxygen. They can also send the cancerous cells through the body to proliferate in other organs, which ultimately causes death. ....

Thomas Huffaker , Ryan Oconnell , Atakan Ekiz , Warren Voth , Cindy Barba , Melanoma Disease Center , Nature Communications , University Of Utah Health , Huntsman Cancer Institute , University Of Utah , National Institutes Of Health Cancer Institute , Oconnell Lab , Huntsman Cancer Foundation , Ryano Connell , Cancer Genome Atlas , National Institutes , National Cancer Institute , ரியான் ஒக்கொண்னேழில் , மெலனோமா நோய் மையம் , இயற்கை தகவல்தொடர்புகள் , பல்கலைக்கழகம் ஆஃப் உட்டா ஆரோக்கியம் , வேட்டைக்காரன் புற்றுநோய் நிறுவனம் , பல்கலைக்கழகம் ஆஃப் உட்டா , தேசிய நிறுவனங்கள் ஆஃப் ஆரோக்கியம் புற்றுநோய் நிறுவனம் , ஒக்கொண்னேழில் ஆய்வகம் , வேட்டைக்காரன் புற்றுநோய் அடித்தளம் ,

New research outlines a critical driver in an immune cell's defense against melanoma

Credit: Huntsman Cancer Institute
SALT LAKE CITY - Today in
Nature Communications, researchers at Huntsman Cancer Institute at the University of Utah report critical new insights into how cells mount an attack against melanoma tumors.
Melanoma is an aggressive type of skin cancer that can arise from excess exposure to sun, frequent sunburns, genetics, and other environmental factors. Melanoma, like all cancers, begins within cells. Specially designed and refined over billions of years, cells are experts at working to root out and fix routine errors that arise. A tumor begins when a cell makes faulty copies of itself over and over again. If left unchecked, these faulty cell copies continue to grow into complex ecosystems that become tumors. Some tumors, like melanomas, can go on to develop mechanisms to sustain themselves with blood flow and oxygen. They can also send the cancerous cells through the body to proliferate in other organs, which ultimately causes death. ....

United States , University Of Utah , Karen Huntsman , Thomas Huffaker , Ryan Oconnell , Atakan Ekiz , Warren Voth , Cindy Barba , Melanoma Disease Center , Nature Communications , University Of Utah Health , National Cancer Institute , Huntsman Cancer Institute , National Institutes Of Health Cancer Institute , Cancer Center , Oconnell Lab , Huntsman Cancer Foundation , Ryano Connell , Cancer Genome Atlas , National Institutes , Cancer Institute , Designated Comprehensive Cancer Center , Mountain West , Utah Population Database , ஒன்றுபட்டது மாநிலங்களில் , பல்கலைக்கழகம் ஆஃப் உட்டா ,

Study confirms racial differences in response to prostate cancer treatment

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DURHAM, N.C. - A study designed to enroll an equal number of Black and white men with advanced prostate cancer confirms key findings that have been evident in retrospective analyses and suggest potential new avenues for treating Black patients who disproportionately die of the disease.
Researchers at Duke Cancer Institute enrolled 50 Black and 50 white men with advanced prostate cancer to test whether there were outcome differences on treatment with the hormone therapy abiraterone acetate plus the steroid prednisone. In retrospective data reviews, the Duke researchers had previously found racial differences in PSA responses among advanced prostate cancer patients. ....

Brendonm Patierno , Mark Fleming , Demonika Anand , Julie Kephart , Andrewj Armstrong , Andrew Armstrong , Dadong Zhang , Patrick Healy , Michael Goodman , Rhonda Wilder , Bonniel Lacroix , James Bearden , A Oliver Sartor , Michaelr Harrison , William Berry , Matthew Milowsky , Jennifera Freedman , Devika Das , Daniel George , Megan Mcnamara , Julia Rasmussen , Alexanderb Sibley , Colleen Riggan , Kellie Shobe , Elisabeth Heath , Terry Hyslop ,

'Information theory' recruited to help scientists find cancer genes

'Information theory' recruited to help scientists find cancer genes
eurekalert.org - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from eurekalert.org Daily Mail and Mail on Sunday newspapers.

United States , Baylor College Of Medicine , Patrick Brown , Weiqiang Zhou , Colin Callahan , Elisabet Pujadas , Garrett Jenkinson , Varenka Rodriguez Diblasi , Johns Hopkins , Challice Bonifant , Adrian Idrizi , Rakel Tryggvadottir , Andrew Feinberg , Jordi Abante , Michael Koldobskiy , John Goutsias , Hongkai Ji , Karenr Rabin , Johns Hopkins University , Bloomberg School Of Public Health , National Institute Of Diabetes , Whiting School Of Engineering , National Institutes Of Health Cancer Institute , Johns Hopkins University School Of Medicine , National Science Foundation , Damon Runyon Cancer Research Foundation ,

Projects & Studies

Projects & Studies
Description
The Acute Effects of Exercise on Breast Cancer Biomarkers (ACE Study) is enrolling women to test the effect of moderate intensity exercise on cancer risk factors such as biomarkers in healthy women. Knowing if exercise significantly alters these biomarkers, could help support guidelines for daily exercise for breast cancer prevention and could indicate that exercise even without weight loss is beneficial.
Advanced Colorectal Cancer of Serrated Subtype (ACCESS) Study
Description
Funding Agency: National Institutes of Health
Advancing our Understanding of the Etiologies and Mutational Landscapes of Basal-like, Luminal A, and Luminal B Breast Cancer
Description
Addressing research gaps in the molecular subtypes of breast cancer, we are taking a multidisciplinary approach to study the epidemiology and mutational landscapes of basal-like, luminal A, and luminal B tumors. ....

University Of Washington , United States , Fred Hutch , Mark Thornquist , Mary Anne Rossing , National Cancer Institute , Research To Optimize The Screening Process , National Institutes Of Health Cancer Institute , Early Detection Research Network , Health Disparities , Colorectal Research In Epidemiology , Infectious Disease Sciences , Personalized Medicine Coalition , Breast Cancer Initiative , Ovary Cancer Clinical Validation Center , Public Health Sciences , Infectious Disease Division , National Institute On Minority Health , University Of Texas Md Anderson Cancer Center , Clinical Trials Network , National Institutes Of Health , Steering Committee , Healthy Community Together We , American Association For Cancer Research , Funding Agency , Acute Effects ,