Microplastics as vectors for contaminants in the environment is becoming a topic of public interest. Microplastics have been found to actively adsorb heavy metals, per-fluorinated alkyl substances (PFAS), polychlorinated biphenyls (PCBs), polyaromatic hydrocarbons (PAHs), pharmaceuticals and personal care products (PPCPs) and polybrominated diethers (PBDs) onto their surface. Particular interest in microplastics capacity to adsorb antibiotics needs further attention due to the potential role this interaction plays on antibiotic resistance. Antibiotic sorption experiments have been documented in the literature, but the data has not yet been critically reviewed. This review aims to comprehensively assess the factors that affect antibiotic sorption onto microplastics. It is recognised that the physico- chemical properties of the polymers, the antibiotic chemical properties, and the properties of the solution all play a crucial role in the antibiotic sorption capacity of microplastics. Wea ....