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In a paper appearing in Nature today, an international group of scientists have unlocked a new way to kill hard to treat cancers. These tumors resist current immunotherapies, including those using Nobel Prize winning check-point blocking antibodies.
E-Mail IMAGE: The front ribbon of the Z-RNA Double-Helix points upwards to the left. In A-RNA and in Watson-Crick B-DNA the foremost ribbon points upwards to the right. Left handed Z-RNA... view more Credit: Alan Herbert In a paper published in the May 13th, 2021 issue of PLOS Genetics, a Z-RNA nanoswitch that regulates interferon immune responses is described. The switch, less than 5 nanometer in length, is based on sequences, called flipons, that change outcomes by altering their three dimensional conformation. The Z-RNA nanoswitch flips from the shorter right-handed A-RNA he...
Social Share The 2021 CARIFTA Junior Chess Championships are in limbo after the Guyana Chess Federation (GCF) declared their inability to host this year’s tournament due to COVID-19 concerns. The GCF wrote officially to the Confederation of Chess for the Americas (CCA) late last month to indicate their social and financial constraints as well as to formally hand over their rights to host the championships. President of the Barbados Chess Federation, Alan Herbert told MIDWEEK SPORT Guyana’s decision is already impacting local players who had their hopes pinned on this year’s champions...