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Study shows overlooked lipid is connected to ancient cellular pathway with links to cancer

Within the family of cell membrane lipids known as phosphoinositides and the kinase enzymes that regulate them, phosphoinositide 3-kinases (PI3Ks) have been cast in a starring role as scientists study their involvement in cancer, diabetes and many cellular activities. ....

Alicia Llorente , Brooke Emerling , Lavinia Palamuc , Archna Ravi , Sanford Burnham Prebys , Vivian Tieu , Lavinia Palamiuc , Thorsten Wiederhold , Sophia Crabtree , Woong Jae Choi , Jaredl Johnson , Gurpreetk Arora , Ryanm Loughran , Jennycy Wong , Rabi Murad , Zeinab Haratipour , Cell Signaling Technology Inc , Vanderbilt University Medical Center , Microenvironment Program At Sanford Burnham Prebys , Science Signaling , Cancer Metabolism , Microenvironment Program , Raymond Blind , Science Advances , Weill Cornell Medicine , Cell Signaling Technology ,

Researchers reveal mechanism by which MAF protein increases metastasis risk in breast cancer patients

Breast cancer is the most common form of cancer among women, with more than 2 million new cases diagnosed each year. In cases where the tumour remains localised in the breast, survival rates are remarkably high, at around 90%. ....

Comunidad Autonoma De Cataluna , Alexandra Avgustinova , Recerca Sant Joan , Mariona Graupera , Alicia Llorente , Roger Gomis , Carme Segura Capellades , Freddy Monteiro , Ingunn Holen , Teresa Blasco , Irene Espuny , Josep Carreras Leukemia Research Institute , Institute For Research , University Of Sheffield , Spanish Ministry Of Science , Caixa Foundation , Health Call , Spanish Association Against Cancer , Nature Cell Biology , Spanish Ministry , Growth Control , Cancer Metastasis , Luciano Di Croce , Genomic Regulation , Antoni Riera , Josep Carreras Leukemia Research ,

Researchers decipher the mechanism by which the MAF protein promotes breast cancer metastasis

Researchers decipher the mechanism by which the MAF protein promotes breast cancer metastasis
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Comunidad Autonoma De Cataluna , Alicia Llorente , Roger Gomis , Nature Cell Biology , Growth Control , Cancer Metastasis ,