Prior spike protein exposures shape protection against SARS-CoV-2 Omicron variant
Researchers found that immune-boosting by SARS-CoV-2 Omicron variant is contingent on prior COVID-19 history.
Source: news-medical.net
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RNA exosomes play a key role in B cell development, UTSW study suggests
New research from UT Southwestern suggests that RNA exosomes – the cellular machines that degrade old molecules of RNA – play a key role in the development of B cells, which are critical to the immune system's ability to protect against infection.
Source: news-medical.net
Treatment with immunity-boosting protein enhances the function of CAR-T cells in fighting blood cancers
Advances in cellular immunotherapy that spur genetically modified T cells to attack cancer cells have revolutionized the treatment of certain blood cancers.
Source: news-medical.net
The effect of Omicron breakthrough infection on the magnitude and breadth of serum neutralizing activity and memory B cells among BNT162b2 vaccinees
Researchers evaluated the impact of breakthrough infections with SARS-CoV-2 Omicron BA.1 sublineage on SARS-CoV-2 variants of concern neutralization and memory B lymphocytes formation among BNT162b2 vaccinees.
Source: news-medical.net
Trial of peptide-centered SARS-CoV-2 T-cell activator in B-cell deficient individuals
A recent phase 1/2 study under review at the Nature Portfolio journal and posted to the Research Square* preprint server demonstrated that a peptide-centered severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) T-cell activator, CoVac-1, was efficient in B-cell deficient people.
Source: news-medical.net