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Studying how X chromosomes are inactivated and reactivated during egg cell development could predict successful egg development and help generate human egg cells in the lab.
Researchers at the Centre for Genomic Regulation in Barcelona have identified a potential new diagnostic marker that predicts the successful and efficient development of mammalian egg cells.
E-Mail IMAGE: Examples of the human oocyte stages used in this study. On the left is an immature GV-stage oocyte recognizable by a visible cell nucleus (white arrow) called germinal vesicle (GV).... view more Credit: Montserrat Barragan/Clinica Eugin Age may adversely affect women's fertility by impairing levels of RNA molecules which in turn alter the function of genes involved in key biological pathways during the final maturation stage of a human egg cell, according to the findings of a new study published today in the journal Aging Cell. Researchers from the Centre for Genomi...