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Synthetic protein quality control system in bacteria


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IMAGE: From left to right, Prof. Sang Woo Seo, Dr. Jina Yang, Mr. Yong Hee Han
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Credit: Seoul National University
On Feb 5th, Seoul National University, College of Engineering (Dean Kookheon Char) announced that Professor Sang Woo Seo s research team (Dr. Jina Yang and Mr. Yong Hee Han (graduate student)) at School of Chemical and Biological Engineering has developed a synthetic protein quality control system to enhance full-length translation in bacteria. This technology is expected to increase the efficiency of the production of biopharmaceuticals, industrial enzymes, and bio-based chemicals.
Recombinant proteins are used in various industrial fields from protein drugs such as insulin to industrial proteins such as laundry detergents. Since proteins can perform their functions only with full-length and proper 3D structure, recombinant protein production using microbial cell factories requires several protein purification steps. To ....

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