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"The regulatory challenge of 3D bioprinting" by Tajanka Mladenovska, Peter F. Choong et al.

New developments in additive manufacturing and regenerative medicine have the potential to radically disrupt the traditional pipelines of therapy development and medical device manufacture. These technologies present a challenge for regulators because traditional regulatory frameworks are designed for mass manufactured therapies, rather than bespoke solutions. 3D bioprinting technologies present another dimension of complexity through the inclusion of living cells in the fabrication process. Herein we overview the challenge of regulating 3D bioprinting in comparison to existing cell therapy products as well as custom-made 3D printed medical devices. We consider a range of specific challenges pertaining to 3D bioprinting in regenerative medicine, including classification, risk, standardization and quality control, as well as technical issues related to the manufacturing process and the incorporated materials and cells. ....

Legal Regulatory , Stem Cells , Tissue Engineering ,

3D bioprinting methods for fabricating bioengineered blood vessel models

A review paper by scientists at the Chonnam National University summarized the recent research on bioprinting methods for fabricating bioengineered blood vessel models. ....

Megan Craig , Hee Gyeong Yi , Chonnam National University , Bionic Systems , Chonnam National , Blood Vessel , N Vitro , Blood Vessels ,

Beyond traditional models: 3D bioprinted tumor microenvironment unlocks resistance insights

Researchers developed a three-dimensional (3D) biologically printed in vitro model of the breast cancer tumor microenvironment. ....

Traksel Shutterstock , Scientific Reports , Breast Cancer , N Vitro ,

Nanoengineered bioink improves tumor model accuracy

Scientists from the Terasaki Institute for Biomedical Innovation have developed a nanoengineered bioink with improved bonding and cross-linking capabilities for 3D bioprinting of tumor models. ....

Ali Khademhosseini , Lily Ramsey , Terasaki Institute For Biomedical Innovation , Terasaki Institute , Biomedical Innovation , Cross Linking , Ene Expression , N Vitro , Pancreatic Cancer ,