Errant DNA boosts immunotherapy effectiveness
E-Mail IMAGE: A UT Southwestern study discovered the molecular mechanism by which tumors defective in DNA mismatch repair respond to immunotherapy. This illustration depicts how cells use a programmed mismatch repair deficiency-activated... view more Credit: Illustration by Yipin Wu DALLAS - Dec. 17, 2020 - DNA that ends up where it doesn't belong in cancer cells can unleash an immune response that makes tumors more susceptible to immunotherapy, the results of two UT Southwestern studies indicate. The findings, published online today in Cancer Cell, suggest that delivering radiat...