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Viral Safety in AAV Production: How Affinity Chromatography Effectively Contributes April 9, 2021 Share Time: 8:00 am PT, 11:00 am ET, 17:00 CET Adeno-associated vectors (AAV) have become the workhorse for gene therapy delivery over the last two decades. With the constantly growing number of clinical trials, the demand for vectors has increased significantly and the need for reliable and scalable manufacturing solutions has emerged. Within this context, the introduction of POROS™ CaptureSelect™ AAV immunoaffinity resins for the capture and purification of AAV vectors resulted in signific...

Be a REBEL with Your Cell Media Analytics March 17, 2021 Time: 8:00 am PT, 11:00 am ET, 17:00 CET Upstream process development labs have historically depended on a core lab to get a picture of changes in critical media nutrients inside a bioreactor. While this became the norm, with results being delivered in weeks rather than days, the data was at least useful enough to inform future endeavors. However, recent breakthroughs in technology have changed that, as it is now possible to obtain a rapid at-line analysis of your cell media to make decisions on the fly. This webinar will introduce a ...

Redesigning CHO: The New Frontier in Bioprocessing? February 18, 2021 Time: 8:00 am PT, 11:00 am ET, 17:00 CET The inherent flexibility and adaptability to bioreactor culture conditions, compared to other mammalian systems, make Chinese hamster ovary (CHO) cell lines the choice system for production of one of the most successful protein therapeutic classes—monoclonal antibodies. Yet, CHO cell line editing for research and commercial purposes can sometimes seem like a minefield, as there are numerous obstacles to face when editing CHO cell lines for optimized protein production. Challenges ...

You may recall that Manny Diaz took the Temple football job and then quit 17 days later to return to Miami. Hard to blame the guy, since his dream job opened up suddenly, but it was a dick move nonetheless to leave the Owls hanging.

This GEN webinar will discuss the real contamination risks described in a recent Nature Biotechnology study and how companies are rising to this challenge through a better selection of components and excipients.