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A new search algorithm has identified 188 kinds of new CRISPR systems in bacterial genomes. The systems have a range of functions and could enable gene editing, diagnostics, and more.
A team of researchers led by Feng Zhang at the McGovern Institute for Brain Research at MIT and the Broad Institute of MIT and Harvard has uncovered the first programmable RNA-guided system in eukaryotes — organisms that include fungi, plants, and an
The first RNA-guided DNA-cutting enzyme found in eukaryotes, Fanzor could one day be harnessed to edit DNA more precisely than CRISPR/Cas systems
A team of researchers led by Feng Zhang at the Broad Institute of MIT and Harvard and the McGovern Institute for Brain Research at MIT has uncovered the first programmable RNA-guided system in eukaryotes — organisms that include fungi, plants, and animals. In a study in Nature, the team describes how the system is based on a protein called Fanzor. They showed that Fanzor proteins use RNA as a guide to target DNA precisely, and that Fanzors can be reprogrammed to edit the genome of human cells. The compact Fanzor systems have the potential to be more easily delivered to cells and tissues as t...
Researchers have discovered the first programmable RNA-guided system discovered in eukaryotes. The technology, known as Fanzor, has the potential to be more easily delivered to cells and tissues than CRISPR-Cas systems, and further refinements could make them a valuable new technology for human genome editing.