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The right combination of bile salt hydrolases may offer a new approach to treat C. diff

Not all probiotics are created equal. In a new study, researchers found that certain enzymes within a class known as bile salt hydrolases (BSHs) can restrict Clostridioides difficile (C. diff.) colonization by both altering existing bile acids and by creating a new class of bile acids within the gut's microbial environment. ....

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Research reveals how microorganisms found in the gut can worsen C. difficile infections

New research from the University of Virginia School of Medicine and collaborators reveals how microorganisms found in our guts can worsen dangerous C. difficile infections. ....

University Of Pennsylvania , United States , Paulac Rangel , Jessical Hart , Alexanderb Smith , Clare Laut , Emily Henderson , Matthew Jenior , Ericp Skaar , Brendanj Kelly , Jessi Erlichman , Robertn Baldassano , Danielr Evans , Emmae Furth , Marwa Abbas , Josephp Zackular , Garym Dunny , Meganl Matthews , Maribethr Nicholson , Jonathan Specker , Katelyna Bustin , Fredericd Bushman , Michaela Silverman , Jennifera Gaddy , Orlaith Keenan , Boonem Prentice ,

Antibiotic-resistant, opportunistic pathogen enhances the pathogenesis of C. difficile

Clostridioides difficile, often referred to as C. difficile or C. diff, is a bacterium that causes severe intestinal illness and, as its name suggests, can be difficult to study and treat. ....

University Of Pennsylvania , United States , Josephp Zackular , Emily Henderson , Laboratory Medicine At Children Hospital Of Philadelphia , University Of Minnesota Medical School , University Of Pittsburgh , University Of Virginia , University Of Florida , Vanderbilt University School Of Medicine , Senior Author , Assistant Professor , Laboratory Medicine , Vanderbilt University School , Minnesota Medical , Amino Acid , C Diff , Gastrointestinal Tract ,

PLF announces See C. Diff campaign

The Peggy Lillis Foundation announced its annual gala to kick off its fourth See C. Diff campaign as part of C. Diff Awareness Month. ....

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Summit Therapeutics Closes Fully-Subscribed $100 Million

Menlo Park, California, Aug. 09, 2022 (GLOBE NEWSWIRE) Summit Therapeutics Inc. (NASDAQ: SMMT) (“Summit,” "we," or the “Company”) today announced the. ....

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