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Inflamed environment is C. diff paradise


Clostridioides difficile (
C. diff) infection gives the pathogen a two-fold advantage: by both creating an inhospitable environment for competing bacteria and providing nutrients that enable
C. diff to thrive.
C. diff is a bacterium that causes diarrhea, often with severe or even fatal consequences. As part of its growth cycle,
C. diff produces two toxins which cause inflammation and damage the lining of the gut.

C. diff thrives when other microbes in the gut are absent - which is why it is more prevalent following antibiotic therapy, says Casey Theriot, associate professor of infectious disease at NC State and corresponding author of the research. But when colonizing the gut, ....

Stephanie Montgomery , Ruthj Parsons , Colleenm Pike , Michaelr Mclaren , Stephaniea Montgomery , Casey Theriot , Matthewh Foley , Joshuar Fletcher , Josh Fletcher , Alissaj Rivera , Caseym Theriot , Nature Communications , National Institutes Of Health , University Of Minnesota , University Of North Carolina Chapel Hill , Carolina State University , North Carolina State University , National Institutes , North Carolina , Chapel Hill , Lineberger Cancer Center , North Carolina Chapel Hill , Medicine Health , மாற்றாந்தாய் மாஂட்கம்ரீ , வழக்கு தேரியட் , ஜோஷ் பிளெட்சர் ,