Antidepressant Use Linked to Increased Risk of Hospital-Onset C Diff
Use of mirtazapine, nortriptyline, and trazodone among hospitalized patients was associated with a greater risk of CDI.
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Use of mirtazapine, nortriptyline, and trazodone among hospitalized patients was associated with a greater risk of CDI.
Age, fecal calprotectin level, toxin B PCR cycle threshold, immunosuppression, sex, and creatinine levels were identified as independent risk factors for developing recurrent CDI.
Social vulnerability index, race, and poverty were associated with increased rates of CDI, calling attention to population-level health disparities.
More than 90% of patients with CDI treated with WMT achieved clinical cure, while only 3.8% of WMTs resulted in adverse events.
Results from the systematic review and meta-analysis showed FMT restored the normal microbiome, reduced the risk of gastrointestinal infections, and did not lead to increased adverse events in patients with HIV.