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Our genetic material is stored in our cells in a specific way to make the meter-long DNA molecule fit into the tiny cell nucleus of each body cell.

Date Time Scientists make DNA breakthrough which could identify why some people are more affected by Covid-19 Scientists from the MRC Weatherall Institute of Molecular Medicine at Oxford University have developed a method that allows them to see, with far greater accuracy, how DNA forms large scale structures within a cell nucleus. This breakthrough will improve understanding of how differences in DNA sequences can lead to increased risks of developing many different diseases. The method, which is around 1000 times more accurate than existing techniques, enables scientists to measure the cont...

Max-Planck-Gesellschaft Our genetic material is stored in our cells in a specific way to make the meter-long DNA molecule fit into the tiny cell nucleus of each body cell. An international team of researchers at the Max Planck Institute for Biology of Ageing, the CECAD Cluster of Excellence in Ageing research at the University of Cologne, the University College London and the University of Michigan have now been able to show that rapamycin, a well-known anti-ageing candidate, targets gut cells specifically to alter the way of DNA storage inside these cells, and thereby promotes gut health and...

It's long been known that people living with HIV experience a loss of white matter in their brains. As opposed to "gray matter," which is composed of the cell bodies of neurons, white matter is made up of a fatty substance called myelin that coats neurons, offering protection and helping them transmit signals quickly and efficiently.

The organization of the human genome relies on physics of different states of matter - such as liquid and solid - a team of scientists has discovered. The findings, which reveal how the physical nature of the genome changes as cells transform to serve specific functions, point to new ways to potentially better understand disease and to create improved therapies for cancer and genetic disorders.