Wistar scientists uncover a key mechanism as to how p53 suppresses tumors
The p53 gene is one of the most important in the human genome: the only role of the p53 protein that this gene encodes is to sense when a tumor is forming and to kill it.
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The p53 gene is one of the most important in the human genome: the only role of the p53 protein that this gene encodes is to sense when a tumor is forming and to kill it.
In a paper published in PNAS, Maureen Murphy, Ph.D., Deputy Director of Wistar's Ellen and Ronald Caplan Cancer Center and Ira Brind Professor and Program Leader in the Molecular & Cellular Oncogenesis Program, and team have identified a gene signature that accurately predicts the functioning of P53 variants, important information to assessing cancer risk and optimizing choices for cancer therapeutics.
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Accomplished cancer researcher supports strategy and expansion of this NCI-designated Cancer CenterPHILADELPHIA, PA, Jan. 13, 2023, has been named Deputy Director of theEllen and Ronald Caplan Cancer Centerat