Mutation or loss of proteins may influence cytoskeleton
Mutation or Loss of Proteins May Influence Cytoskeleton by Angela Mohan on December 28, 2020 at 12:25 PM SETD2 is a protein that helps turn genes on or off by modifying histone proteins in the nucleus of the cell. When SETD2 is mutated or lost in clear-cell renal cell carcinoma, researchers turned toward SETD2 function in the nucleus of the cell to explain various cancers. In 2016, the lab of Dr. Cheryl Walker, director of the Center for Precision Environmental Health at Baylor College of Medicine, discovered that SETD2 not only remodels chromosomes in the nucleus but also...