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Ludwig Cancer research study finds way to revive potent immune cells for cancer therapy

Credit: Ludwig Cancer Research
MAY 24, 2021, NEW YORK - A Ludwig Cancer Research study has discovered how to revive a powerful but functionally inert subset of anti-cancer immune cells that are often found within tumors for cancer therapy.
Led by Ludwig Lausanne s Ping-Chih Ho and Li Tang of the École Polytechnique Fédérale de Lausanne, the study describes how an immune factor known as interleukin-10 orchestrates the functional revival of terminally exhausted tumor-infiltrating T lymphocytes (TILs), which have so far proved impervious to stimulation by immunotherapies. It also demonstrates that the factor, when applied in combination with cell therapies, can eliminate tumors in mouse models of melanoma and colon cancer. The findings are reported in the current issue of ....

Chih Ho , Li Tang , Fondation Pierre Mercier , Swiss Institute For Experimental Cancer Research , Cancer Research Institute , Technology Of The People Republic China , A Ludwig Cancer Research , Ludwig Cancer Research , Chinese Academy Of Sciences , Swiss National Science , Kristian Gerhard Jebsen Foundation , Biltema Foundation , Chinese Scholarship Council , European Research Council , University Of Lausanne , Ludwig Institute For Cancer Research , Swiss Cancer League , Ministry Of Science , Ludwig Lausanne , Ludwig Institute , Cancer Research , Associate Member , Lausanne Branch , Associate Professor , Swiss Institute , Experimental Cancer Research ,

Ludwig Cancer Research study discovers how to revive potent but inert anti-cancer immune cells for therapy

MAY 24, 2021, NEW YORK - A Ludwig Cancer Research study has discovered how to revive a powerful but functionally inert subset of anti-cancer immune cells. ....

Chih Ho , Li Tang , Fondation Pierre Mercier , Swiss Institute For Experimental Cancer Research , Cancer Research Institute , Technology Of The People Republic China , A Ludwig Cancer Research , Ludwig Cancer Research , Chinese Academy Of Sciences , Swiss National Science , Kristian Gerhard Jebsen Foundation , Biltema Foundation , Chinese Scholarship Council , European Research Council , University Of Lausanne , Ludwig Institute For Cancer Research , Swiss Cancer League , Ministry Of Science , Ludwig Lausanne , Ludwig Institute , Cancer Research , Associate Member , Lausanne Branch , Associate Professor , Swiss National , Swiss Institute ,