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Acurx's ibezapolstat posts positive phase II data but stock slips

Acurx Pharmaceuticals Inc. continues to post positive data for its lead candidate ibezapolstat but that didn’t stop the stock from tumbling. The antibiotic outperformed vancomycin in a phase IIb study treating Clostridioides difficile infection (CDI). Vancomycin is a standard of care in the indication. Ibezapolstat eradicated fecal CDI at day 3 in 15 of 16 patients compared to vancomycin, which eradicated fecal CDI in 10 of 14 patients. ....

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Lirentelimab out on failed phase II data; Allakos restructures

Allakos Inc. terminated all development of its lead drug, anti-Siglec-8 antibody lirentelimab (AK-002), and is cutting its workforce in half, following phase II failures for atopic dermatitis and chronic spontaneous urticaria. The San Carlos, Calif.-based company will now focus on phase I trials for anti-Siglec-6 antibody AK-006 as part of a restructuring that stretches the runway into mid-2026. Shares (NASDAQ:ALLK) sank by 60.2%, down $1.80, to close at $1.19 on Jan. 16. ....

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FOXNEWS Jesse Watters Primetime June 4, 2024 06:51:00

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The transfer that adds an element of anger to the League of Ireland title race

Nature of Pat Hoban’s exit from Dundalk provides a new dimension to Derry City’s challenge. ....

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N4 Pharma reports progress in Nuvec clinical research

Pharmaceutical delivery system developer N4 Pharma reported significant progress in its research efforts to enhance viral vector performance using Nuvec on Monday. ....

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