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The largest brain cell 'atlas' to date could help improve our understanding of neuropsychiatric conditions, such as schizophrenia, bipolar disorder, Alzheimer’s disease, and major depression.
Researchers say the disruption of 12-hour patterns of cyclic gene activity in the brain may be a factor in the development of schizophrenia
Stem cell engineering used to identify gene signaling pathway linked to schizophrenia Using human-induced pluripotent stem cells engineered from a single family's blood samples, a gene signaling pathway linked to a higher risk for developing schizophrenia was discovered by scientists at The University of Texas Health Science Center at Houston (UTHealth). The research was published in a recent issue of Neuropsychopharmacology. The signaling pathway researchers pinpointed is called phosphoinositide 3-kinase/glycogen synthase kinase 3 (PI3K/GSK3). Among the differentially expressed genes along ...
E-Mail Credit: (Photo by Laura Stertz, PhD/UTHealth) Using human-induced pluripotent stem cells engineered from a single family's blood samples, a gene signaling pathway linked to a higher risk for developing schizophrenia was discovered by scientists at The University of Texas Health Science Center at Houston (UTHealth). The research was published in a recent issue of Neuropsychopharmacology. The signaling pathway researchers pinpointed is called phosphoinositide 3-kinase/glycogen synthase kinase 3 (PI3K/GSK3). Among the differentially expressed genes along the pathway was one called seru...