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RESPONSE: Seladelpar Normalizes Alkaline Phosphatase, Reduces Pruritus in PBC

Published: February 22, 2024

Results from the phase 3 trial showed seladelpar elicited biochemical response, normalized alkaline phosphatase, and reduced pruritus at a greater rate than placebo.

Source: hcplive.com

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David AssisTerry HornerGideon HirschfieldYale School Of MedicineAutoimmune Liver Disease ResearchDrug AdministrationUniversity Of TorontoFoundation Gideon HirschfieldNew England JournalYale SchoolCymabay Therapeutic New Drug ApplicationPriority ReviewPrescription Drug User Fee ActTerry Horner ChairPrimary BiliaryImproves MarkersSecond Line TreatmentPrimary Biliary CholangitisBiochemical ResponseAlkaline PhosphataseUrsodeoxycholic AcidObeticholic Acid