Autophagy Protein Beclin-1 Essential for Pregnancy Establishment
Beclin-1-mediated autophagy acts as a molecular switch that governs the early uterine morphogenetic program by maintaining the endometrial progenitor stem cells.
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Beclin-1-mediated autophagy acts as a molecular switch that governs the early uterine morphogenetic program by maintaining the endometrial progenitor stem cells.
Throughout a woman's reproductive life, the endometrium, the mucous membrane lining the uterus, goes through cyclical remodeling. It thickens during the menstrual cycle in preparation for embryo implantation, and it is shed during menstruation when there is no fertilization.
Emonet was recently appointed the Lewis B. Cullman Professor of Molecular, Cellular and Developmental Biology and Professor of Physics.
A University of Pennsylvania–led team coaxed stem cells to take on the characteristics and functions of a human adrenal gland, progress that could lead to new therapies for adrenal insufficiencies.
A team coaxed stem cells to take on the characteristics and functions of a human adrenal gland, progress that could lead to new therapies for adrenal insufficiencies and a deeper understanding of the genetics of such disorders.