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The FDA approved crizotinib for treatment of adults and children aged 1 year or older with anaplastic lymphoma kinase-positive unresectable, recurrent or refractory inflammatory myofibroblastic tumors. Crizotinib (Xalkori, Pfizer), an ALK tyrosine kinase inhibitor, is approved for treatment of patients with metastatic non-small cell lung cancer whose tumors are ALK positive or ROS1 positive, as

A veteran Chittenden County deputy sheriff, Lt. Dan Gamelin, is running for the department’s top post following the announced retirement of Sheriff Kevin McLaughlin.

CHICAGO — The addition of panitumumab vs. bevacizumab to standard doublet chemotherapy significantly extended survival among patients with RAS wild-type and left-sided metastatic colorectal cancer, according to study results.The panitumumab (Vectibix, Amgen) regimen conferred median OS of more than 3 years —— the longest survival ever reported in a first-line, prospective phase

Hispanic children with high-risk neuroblastoma had worse survival outcomes than other children with the disease despite receiving treatment on clinical trials with standardized protocols, according to study results.Researchers observed the disparities even after controlling for disease-related factors.