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Clinical Challenges: Using Pola-R-CHP for Diffuse Large B-Cell Lymphoma

Regimen is approved for frontline treatment, but when it represents the best choice is less clear

Philadelphia , Pennsylvania , United-states , Tampa , Florida , Delaware , Leah-lawrence , Jakub-svoboda , Michael-jain , Moffitt-cancer-center , National-comprehensive-cancer-network , Penn-medicine

Bispecific Antibodies in DLBCL: Therapeutic Potential

Robert Mancini, PharmD, discusses current DLBCL (diffuse large B cell lymphoma) management approaches, relapse rates, frontline, and subsequent therapies, including emerging treatments like bispecific T-cell engagers and monoclonal antibodies.

Robert-mancini , Emerging-role , Bispecific-antibodies , Diffuse-largeb-cell-lymphoma-management , Diffuse-largeb-cell-lymphoma , Dlbcl , Immunotherapy , Clinical-effectiveness , Safety-profiles , Ultidisciplinary-care , Therapy-approaches

Odronextamab Exhibits Continued Clinical Activity and Tolerable Safety Profile in R/R DLBCL

Odronextamab produced durable responses and a generally manageable safety profile in patients with relapsed/refractory diffuse large B-cell lymphoma.

Sabarish-ram-ayyappan , Regeneron-pharmaceuticals , European-organization-for-research-of-cancer , City-of-hope-cancer-treatment-center , Ram-ayyappan , Hope-cancer-treatment-center , European-organization , Ann-arbor , Prescription-drug-user-fee-act , Diffuse-largeb-cell-lymphoma , Follicular-lymphoma

NX-1607 Is Under Phase 1 Evaluation in DLBCL and Other Advanced Malignancies

The phase 1a/1b NX-1607-101 trial will evaluate NX-1607, a CBL-B inhibitor, in patients with advanced malignancies, including diffuse large B-cell lymphoma.

United-states , United-kingdom , Nx-1607-101-trial- , Nx-1607 , Patients-with-advanced-malignancies , Diffuse-largeb-cell-lymphoma , Nct05107674 ,

Updated Odronextamab Data from Relapsed/Refractory Diffuse

Updated Odronextamab Data from Relapsed/Refractory Diffuse
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United-states , San-diego , California , American , Sabarish-ram-ayyappan , Tammy-allen , Jone-arnason , International-prognosis-index , Nasdaq , European-medicines-agency , European-union , American-society-of-hematology

Updated Odronextamab Data from Relapsed/Refractory Diffuse Large B-cell Lymphoma Pivotal Trial Showed Deep and Durable Responses and the Potential of ctDNA To Predict Long-term Outcomes

Updated Odronextamab Data from Relapsed/Refractory Diffuse Large B-cell Lymphoma Pivotal Trial Showed Deep and Durable Responses and the Potential of ctDNA To Predict Long-term Outcomes
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United-states , San-diego , California , American , Vesna-tosic , Tammy-allen , Jone-arnason , Sabarish-ram-ayyappan , Linkedin , Beth-israel-deaconess-medical-center , European-union , International-prognosis-index

Updated Odronextamab Data From Relapsed/Refractory Diffuse Large B-Cell Lymphoma Pivotal Trial Showed Deep And Durable Responses And The Potential Of ...

Updated Odronextamab Data From Relapsed/Refractory Diffuse Large B-Cell Lymphoma Pivotal Trial Showed Deep And Durable Responses And The Potential Of ...
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United-states , San-diego , California , American , Sabarish-ram-ayyappan , Jone-arnason , Beth-israel-deaconess-medical-center , International-prognosis-index , Drug-administration , European-union , Odronextamab-clinical-program , Regeneron-pharmaceuticals-inc

Updated Odronextamab Data from Relapsed/Refractory Diffuse Large B-cell Lymphoma Pivotal Trial Showed Deep and Durable Responses and the Potential of ctDNA To Predict Long-term Outcomes

Phase 2 primary analysis results presented in ASH oral session demonstrated a 52% objective response rate , with 31% achieving a complete response Results from a Phase 1 expansion cohort showed a...

United-states , San-diego , California , American , Jone-arnason , Vesna-tosic , Sabarish-ram-ayyappan , Tammy-allen , Drug-administration , International-prognosis-index , Nasdaq , Regeneron-genetics-center

Updated Odronextamab Data from Relapsed/Refractory Diffuse Large B-cell Lymphoma Pivotal Trial Showed Deep and Durable Responses and the Potential of ctDNA To Predict Long-term Outcomes

Updated Odronextamab Data from Relapsed/Refractory Diffuse Large B-cell Lymphoma Pivotal Trial Showed Deep and Durable Responses and the Potential of ctDNA To Predict Long-term Outcomes
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United-states , San-diego , California , American , Tammy-allen , Jone-arnason , Sabarish-ram-ayyappan , Vesna-tosic , International-prognosis-index , European-medicines-agency , European-union , Drug-administration

Updated Odronextamab Data from Relapsed/Refractory Diffuse Large B-cell Lymphoma Pivotal Trial Showed Deep and Durable Responses and the Potential of ctDNA To Predict Long-term Outcomes

Phase 2 primary analysis results presented in ASH oral session demonstrated a 52% objective response rate , with 31% achieving a complete response Results from a Phase 1 expansion cohort showed a...

United-states , San-diego , California , American , Sabarish-ram-ayyappan , Jone-arnason , Tammy-allen , Vesna-tosic , Beth-israel-deaconess-medical-center , Odronextamab-clinical-program , International-prognosis-index , American-society-of-hematology