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"Translocation and fate of nanospheres in pheochromocytoma cells follow" by Palalle G.Tharushi Perera, Zoltan Vilagosh et al. - Vimarsana News

"Translocation and fate of nanospheres in pheochromocytoma cells follow" by Palalle G.Tharushi Perera, Zoltan Vilagosh et al.

The routes by which foreign objects enter cells is well studied; however, their fate following uptake has not been explored extensively. Following exposure to synchrotron-sourced (SS) terahertz (THz) radiation, reversible membrane permeability has been demonstrated in eukaryotic cells by the uptake of nanospheres; nonetheless, cellular localization of the nanospheres remained unclear. This study utilized silica core-shell gold nanospheres (AuSi NS) of diameter 50 ± 5 nm to investigate the fate of nanospheres inside pheochromocytoma (PC 12) cells following SS THz exposure. Fluorescence microsc...

Source: uow.edu.au
"Localization of nanospheres in pheochromocytoma-like cells following e" by Palalle G. Tharushi Perera, Denver P. Linklater et al. - Vimarsana News

"Localization of nanospheres in pheochromocytoma-like cells following e" by Palalle G. Tharushi Perera, Denver P. Linklater et al.

Exposure to high-frequency (HF) electromagnetic fields (EMFs) at 18 GHz was previously found to induce reversible cell permeabilization in eukaryotic cells; however, the fate of internalized foreign objects inside the cell remains unclear. Here, silica core-shell gold nanospheres (Au NS) of 20 ± 5 nm diameter were used to study the localization of Au NS in pheochromocytoma (PC 12) cells after exposure to HF EMFs at 18 GHz. Internalization of Au NS was confirmed using fluorescence microscopy and transmission electron microscopy. Analysis based on corresponding scanning transmission electron mi...

Source: uow.edu.au