Cochrane Review Calls for More Research on Antidepressant Withdrawal Researchers find a lack of current literature on safe, effective ways to manage antidepressant withdrawal and make suggestions for future research. 15 A new Cochrane review examines the current body of research on stopping antidepressant use, finding a major lack in this area. The researchers call for further investigation into safe and effective strategies for stopping antidepressants. “We know the rise in long-term antidepressant use is a major concern around the world,” says lead review author and Belgian-based resea...