Identification of Alzheimer's disease-associated micro-RNA biomarkers through network-based analysis
Micro-ribonucleic acids (miRNAs) linked to cognition and Alzheimer's disease (AD).
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Micro-ribonucleic acids (miRNAs) linked to cognition and Alzheimer's disease (AD).
The study published in Nature Cardiovascular Research reveals that SARS-CoV-2, the virus causing COVID-19, can directly infect coronary vessels and arterial plaques, heightening the risk of cardiovascular complications like heart attacks and strokes. These findings offer critical insights into the increased long-term cardiovascular risks for COVID-19 survivors and open new avenues for targeted therapies.
Two nationally recognized experts in cloning and stem cell science from the University of Houston, Wa Xian and Frank McKeon, are reporting that five lung stem cell variants dominate the lungs of patients with advanced cystic fibrosis (CF), and that these variants drive key aspects of CF pathology including inflammation, fibrosis and mucin secretion.
Researchers have developed BigRNA, a groundbreaking deep learning model capable of predicting RNA behavior, including tissue-specific expression and splicing, directly from genomic DNA sequences. The model excels in identifying pathogenic variants and could be a game-changer in the development of personalized RNA-based therapies for treating genetic diseases.
A Ludwig Cancer Research study has for the first time exhaustively analyzed immune cells known as neutrophils that reside in brain tumors, including gliomas, which develop in the brain itself, and cancers that spread there from the lung, breast and skin.