"What Constitutes a Clear Margin in Patients with Locally Recurrent Rec" by Cherry E. Koh, Kilian G.M. Brown et al.
Objectives: To determine what constitutes a clear resection margin (R0) in patients with LRRC. Summary of Background Data: R0 is the most important predictor of survival in patients with LRRC. However, it is not clear what constitutes an R0. A 1-2mm margin is often used to define R0 but this is based on primary rectal cancer studies. The same definition of R0 is likely inappropriate considering the anatomy and etiology of local recurrences. Methods: A prospective maintained database was reviewed. A R2 margin was defined as macroscopic residual disease. R1 was defined as a microscopically invol...
Source: uow.edu.au