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Using blood pressure medications to lower the top number of blood pressure reading (systolic blood pressure) may not be safe or effective among people who have an acute ischemic stroke and undergo a successful mechanical clot removal — endovascular therapy, according to a phase-2 late-breaking clinical trial presented today at the American Stroke Association's International Stroke Conference 2023.

There doesn’t appear to be a reason to artificially lower BP in this scenario, unless the systolic reading climbs above 180 mm Hg.

When conducting clinical research, investigators aim to control as many variables as possible so it is easier to examine the effectiveness of new treatments.

Aiming for a systolic BP below 120 mm Hg instead of 140-180 mm Hg worsened functional outcomes at 90 days.

UC’s Mistry leads BEST-II clinical trial, attends leadership forum