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It in 2008. prescription drug abuse is the most rampant after that. cocaine is the third most popular. and the active ingredient in ecstasy is fourth. crack is at the bottom of the list. fifth. more than a million used it in 2008. methamphetamine and lsd tied for the sixth spot. heroin the 8th most used drug. calling mexican cartels the single great ef drug threat to the united states. they've turned the city juarez into a war zone. it's made the city's mayor a marked man. cnn's gary tuchman spent time there. >> reporter: more than 2,600 people were murdered in juarez, mexico last year. highes...

The shooter has been identified as bill just said, 64-year-old stephen paddock who had been in his room at the mandalay bay resort since september 28th he just revealed. who knows if he had ever left that room or didn't let made staff in that room. but that's what we were just told. and we were also told he was known to local police. and it was just confirmed he died at the scene. he took his own life as police entered his room. >> bill: multiple weapons. 10 rifles found inside the room. fired hundreds of rounds into the crowd. a female person of interest who may have been with him at the time...